Research Units
Analytical Chemistry Unit

Analytical Chemistry Unit

PAIDI Group in the Unit:

This unit investigates the development and application of quality control methodologies aimed at the detection of organic contaminants (such as pesticide residues) and other compounds of interest in food industry, specially, in olive oil, olives and by-products of this sector. For this reason, one of its fundamental lines of research consists of developing scientific instruments to improve the productive capacity of analysis laboratories.


Bouza, M., Ahlmann, N., García Reyes, J.F., & Franzke, J. (2023). Solvent-assisted laser desorption flexible microtube plasma mass spectrometry for direct analysis of dried samples on paper. Analytical Chemistry, 95(50), 18370-18378. 

Bouza, M., Ahmed, E., Rocío Bautista, P., Brandt, S., Franzke, J., Molina Díaz, A., García Reyes, J.F., & Donald, W.A. (2023). Ion heating in advanced dielectric barrier discharge ion sources for ambient mass spectrometry. Journal of the American Society for Mass Spectrometry, 34(6), 1145-1152.

Bouza, M., García Martínez, J., Gilbert López, B., Brandt, S., García Reyes, J.F., Molina Díaz, A., & Franzke, J. (2023). Dielectric barrier discharge ionization mechanisms: Polycyclic aromatic hidrocarbons as a case of study. Analytical Chemistry, 95(2), 854-861. 

Caño Carrillo, I., Gilbert López, B., Montero, L., Martínez Piernas, A.B., García Reyes, J.F., & Molina Díaz, A. (2023). Comprehensive and heart-cutting multidimensional liquid chromatography-mass spectrometry and its applications in food analysis. Mass Spectrometry Reviews, 2023. 

Gila, A.M., Aguilera, M.P., Sánchez-Ortiz, A., Jiménez, A., & Beltrán, G. (2023). A rapid estimation of pigment content in virgin olive oils by a solvent-free method. European Journal of Lipid Science and Technology, 125(10), Article 2300042. 

Palacios Colon, L., Rascón, A.J., & Ballesteros, E. (2023). Determination of parabens and phenolic compounds in dairy products through the use of a two-step continuous SPE system including an enhanced matrix removal sorbent in combination with UHPLC-MS/MS. Foods, 12(15), Article 2909. 

Palacios Colon, L., Rascón, A.J., & Ballesteros, E. (2023). Simultaneous determination of phenolic pollutants in diary product held in various types of packaging by gas chromatography-mass spectrometry. Food Control, 146, Article 109564. 

Rascón, A.J., Rocío Bautista, P., Moreno González, D., García Reyes, J.F., & Ballesteros, E. (2023). Fiber coating based on a green metal-organic framework to determine phthalates in bottled waters by direct-immersion micro solid-phase extraction. Microchemical Journal, 191, Article 108767. 

Rascón, A.J., Rocío Bautista, P., Palacios Colón, L., & Ballesteros, E. (2023). Easy determination of benzophenone and its deriatives in sunscreen samples by direct-immersion solid-phase microextraction and gas chromatography-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 236, Article 115711. 


Bartella, L., Bouza, M., Rocío-Bautista, P., Di Donna, L., García-Reyes, J.F., & Molina-Díaz, A. (2022). Direct wine profiling by mass spectrometry (MS): A comparison of different ambient MS approaches. Microchemical Journal, 179, Article 107479.

Chafi, S., Azzouz, A., & Ballesteros, E. (2022). Occurrence and distribution of endocrine disrupting chemicals and pharmaceuticals in the river Bouregreg (Rabat, Morocco). Chemosphere, 287(Pt 2), Article 132202.

Chafi, S., & Ballesteros, E. (2022). A sensitive, robust method for determining natural and synthetic hormones in surface and wastewaters by continuous solid-phase extraction–gas chromatography–mass spectrometry. Environmental Science and Pollution Research International, 29(35), 53619-53632.

Gila, A., Aguilera, M.P., Sánchez-Ortiz, A., Jiménez, A., & Beltrán, G. (2022). Effect of centrifugal force (G) on stability of natural emulsions (water/oil) present in fresh virgin olive oils. Journal of Food Engineering, 334, Article 111169.

Palacios Colón, L., Rascón, A.J., & Ballesteros, E. (2022). Trace-Level Determination of Polycyclic Aromatic Hydrocarbons in Dairy Products Available in Spanish Supermarkets by Semi-Automated Solid-Phase Extraction and Gas Chromatography–Mass Spectrometry Detection. Foods, 11(5), Article 713.

Riasová, P., Jenčo, J., Moreno-González, D., Vander Heyden, Y., Mangelings, D., Polášek, M., & Jáč, P. (2022). Development of a capillary electrophoresis method for the separation of flavonolignans in silymarin complex. Electrophoresis, 43(9-10), 930-938.


Beltrán, G., Bejaoui, M.A., Sánchez-Ortiz, A., & Jiménez, A. (2021). Water addition during oil extraction affects on virgin olive oil etanol content, quality and composition. European Journal of Lipid Science and Technology, 123(11), Article 2000400.

Beltrán, G., Hueso, A., Bejaoui, M.A., Gila, A.M., Costales, R., Sánchez-Ortiz, A., Aguilera, M.P., & Jiménez, A. (2021). How olive washing and storage affect fruit ethanol and virgin olive oil ethanol, ethyl esters and composition. Journal of the science of food and agriculture, 101(9), 3714–3722.

Bouza, M., Gilbert-López, B., García-Reyes, J.F., & Rodríguez Ortega, P.G. (2021). Measuring the mass of an electron: an undergraduate laboratory experiment with high resolution mass spectrometry. Chemistry Teacher International, 4(1), 15-22.

Castilla-Fernández, D., Moreno-González, D., Bouza, M., Saez-Gómez, A., Ballesteros, E., García-Reyes, J.F., & Molina-Díaz, A. (2021). Assessment of a specific sample cleanup for the multiresidue determination of veterinary drugs and pesticides in salmon using liquid chromatography/tandem mass spectrometry. Food Control, 130, Article 108311.

Castilla-Fernández, D., Moreno-González, D., García-Reyes, J.F., Ballesteros, E., & Molina-Díaz, A. (2021). Determination of atropine and scopolamine in spinach-based products contaminated with Genus datura by UHPLC–MS/MS. Food Chemistry, 347, Article 129020.

Castilla-Fernández, D., Moreno-González, D., Gilbert-López, B., García-Reyes, J.F., & Molina-Díaz, A. (2021). Worldwide survey of pesticide residues in citrus-flavored soft drinks. Food Chemistry, 365, Article 130486.

Castilla-Fernández, D., Moreno-González, D., Murillo-Cruz, M.C., García-Reyes, J.F., & Molina-Díaz, A. (2021). Appraisal of different clean-up strategies for the determination of fipronil and its metabolites in eggs by UHPLC-MS/MS. Microchemical Journal, 166, Article 106275.

Gila, A., Sánchez-Ortiz, A., Jiménez, A., & Beltrán, G. (2021). The ultrasound application does not affect to the thermal properties and chemical composition of virgin olive oils. Ultrasonics sonochemistry, 70, Article 105320.

Hejji, L., Azzouz, A., Palacios Colón, L., Souhail, B., & Ballesteros, E. (2021). A multi-residue method for determining twenty-four endocrine disrupting chemicals in vegetables and fruits using ultrasound-assisted solid–liquid extraction and continuous solid-phase extraction. Chemosphere, 263, Article 128158.

Moreno-González, D., Castilla-Fernández, D., Vogel, P., Niu, G., Brandt, S., Drees, C., García-Reyes, J.F., Molina-Díaz, A., & Franzke, J. (2021). Evaluation of a novel controlled-atmosphere flexible microtube plasma soft ionization source for the determination of BTEX in olive oil by headspace-gas chromatography/mass spectrometry. Analytica Chimica Acta, 1179, Article 338835.

Palacios Colón, L., Rascón, A.J., Hejji, L., Azzouz, A., & Ballesteros, E. (2021). Validation and use of an accurate, sensitive method for sample preparation and gas chromatography–mass  spectrometry determination of different endocrine-disrupting chemicals in dairy products. Foods, 10(5), Article 1040.


Azzouz, A., Palacios-Colón, L., Hejji, L., & Ballesteros-Tribaldo, E.A. (2020). Determination of alkylphenols, phenylphenols, bisphenol A, parabens, organophosphorus pesticides and triclosan in different cereal-based foodstuffs by gas chromatography-mass spectrometry. Analytical and Bioanalytical Chemistry, 412, 2621-2631.

Beneito-Cambra, M., Gilbert-López, B., Moreno-González, D., Bouza, M., Franzke, J., García-Reyes, J.F., & Molina-Díaz, A. (2020). Ambient (desorption/ionization) mass spectrometry methods for pesticide testing in food: a review. Analytical Methods: Advancing Methods and Applications, 12(40), Article 4831-4852.

Beneito-Cambra, M., Moreno-González, D., García-Reyes, J.F., Bouza, M., Gilbert-López, B., & Molina-Díaz, A. (2020). Direct analysis of olive oil and other vegetable oils by mass spectrometry: A review. TrAC Trends in Analytical Chemistry, 132, Article 116046.

Bourebaba, L., Gilbert-López, B., Oukil, N., & Bedjou, F. (2020). Phytochemical composition of Ecballium elaterium extracts with antioxidant and anti-inflammatory activities: Comparison among leaves, flowers and fruits extracts. Arabian Journal of Chemistry, 13(1), 3286-3300.

Cuadros-Rodríguez, L., Lazúen-Muros, M., Ruiz-Samblás, C., & Navas-Iglesias, N. (2020). Leachables from plastic materials in contact with drugs. State of the art and review of current analytical approaches. International journal of pharmaceutics, 583, Article 119332.

Gila, A., Bejaoui, M.A., Beltrán, G., & Jiménez, A. (2020). Rapid method based on computer vision to determine the moisture and insoluble impurities content in virgin olive oils. Food control, 113, Article 107210.

Gila, A., Sánchez-Ortíz, A., Beltrán, G., Bejaoui, M.A., Aguilera, M.P., & Jiménez, A. (2020). Effect of clarification system on the conservation of virgin olive oil during its storage. European Journal of Lipid Science and Technology, 122(4), Article 1900426.

Jáč, P., Bubáková, Z., Moreno-González, D., Kováčová, G., Špulák, M., & Polášek, M. (2020). Stability study of -bromophenylacetic acid: Does it represent an appropriate model analyte for chiral separations? Electrophoresis, 41(18-19), 1557-1563.

Karttunen, A.P., Poms, J., Sacher, S., Sparén, A., Ruiz Samblás, C., Fransson, M., Martin De Juan, L., Remmelgas, J., Wikström, H., Hsiao, W.K., Folestad, S., Korhonen, O., Abrahmsén-Alami, S., & Tajarobi, P. (2020). Robustness of a continuous direct compression line against disturbances in feeding. International journal of pharmaceutics, 574, Article 118882.

Knodel, A., Foest, D., Brandt, S., Ahlmann, N., Marggraf, U., Gilbert-López, B., & Franzke, J. (2020). Detection and Evaluation of Lipid Classes and Other Hydrophobic Compounds Using a Laser Desorption/Plasma Ionization Interface. Analytical Chemistry, 92(22), 15212-15220.

Knodel, A., Marggraf, U., Ahlmann, N., Brandt, S., Foest, D., Gilbert-López, B., & Franzke, J. (2020). Standardization of sandwich-structured Cu-Glass substrates embedded in a flexible diode laser-plasma interface for the detection of cholesterol. Analytical Chemistry, 92(6), 4663-4671.

Mata-Pérez, C., Padilla-Serrano, M.N., Sánchez-Calvo, B., Begara-Morales, J.C., Valderrama-Rodríguez, R., Chaki, M., Aranda-Caño, L., Moreno-González, D., Molina-Díaz, A., & Barroso-Albarracín, J.B. (2020). Endogenous Biosynthesis of S-Nitrosoglutathione From Nitro-Fatty Acids in Plants. Frontiers in Plant Science, 11, Article 962.

Michael, S.G., Michael-Kordatou, I., Nahim-Granados, S., Polo-López, M.I., Rocha, J., Martínez-Piernas, A.B., Fernández-Ibáñez, P., Agüera-López, A., Manaia, C.M., & Fatta-Kassinos, D. (2020). Investigating the impact of UV-C/H2O2 and sunlight/H2O2 on the removal of antibiotics, antibiotic resistance determinants and toxicity present in urban wastewater. Chemical Engineering Journal, 388, Article 124383.

Moreno-González, D., Cutillas, V., Hernando, M.D., Alcántara-Durán, J., García-Reyes, J.F., & Molina-Díaz, A. (2020). Quantitative determination of pesticide residues in specific parts of bee specimens by nanoflow liquid chromatography high resolution mass spectrometry. The Science of the Total Environment, 715, Article 137005.

Moreno-González, D., Jáč, P., Švec, F., & Nováková, L. (2020). Determination of Sudan dyes in chili products by micellar electrokinetic chromatography-MS/MS using a volatile surfactant. Food chemistry, 310, Article 125963.

Muñoz-Almagro, N., Gilbert-López, B., Pozuelo-Rollón, M.C., García-Fernández, Y., Almeida, C., Villamiel, M., Mendiola, J.A., & Ibáñez, E. (2020). Exploring the Microalga Euglena cantabrica by Pressurized Liquid Extraction to Obtain Bioactive Compounds. Marine Drugs, 18(6), Article 308.

Rocío-Bautista, P., Famiglini, G., Termopoli, V., Palma, P., Nazdrajić, E., Pawliszyn, J., & Cappiello, A. (2020). Direct coupling of Bio-SPME to liquid electron ionization-MS/MS via a modified microfluidic open interface. Journal of the American Society for Mass Spectrometry, 32(1), 262-269.

Rocio-Bautista, P., Gutiérrez-Serpa, A., Cruz, A.J., Ameloot, R., Ayala, J.H., Afonso, A.M., Pasán, J., Rodríguez-Hermida, S., & Pino, V. (2020). Solid-phase microextraction coatings based on the metal-organic framework ZIF-8: Ensuring stable and reusable fibers. Talanta, 215, Article 120910.

Termopoli, V., Famiglini, G., Vocale, P., Morini, G.L., Palma, P., Rocío-Bautista, P., Saeed, M., Perry, S., & Cappiello, A. (2020). Microfluidic water-assisted trap focusing method for ultra-large volume injection in reversed-phase nano-liquid chromatography coupled to electron ionization tandem-mass spectrometry. Journal of Chromatography A, 1627, Article 461421.

Vogel, P., Lazarou, C., Gazeli, O., Brandt, S., Franzke, J., & Moreno-González, D. (2020). Study of Controlled Atmosphere Flexible Microtube Plasma Soft Ionization Mass Spectrometry for Detection of Volatile Organic Compounds as Potential Biomarkers in Saliva for Cancer. Analytical Chemistry, 92(14), 9722-9729.


Alcántara-Durán, J., Moreno-González, D., García-Reyes, J.F., & Molina-Díaz, A. (2019). Use of a modified QuEChERS method for the determination of mycotoxin residues in edible nuts by nano flow liquid chromatography high resolution mass spectrometry. Food Chemistry, 279, 144-149.

Azzouz, A., Goud, K.Y., Raza, N., Ballesteros, E., Lee, S-E., Hong, J., Deep, A., & Kim, K-H. (2019). Nanomaterial-based electrochemical sensors for the detection of neurochemicals in biological matrices. Trends in Analytical Chemistry, 110, 15-34.

Castilla-Fernández, D., Moreno-González, D., Beneito-Cambra, M., & Molina-Díaz, A. (2019). Critical assessment of two sample treatment methods for multiresidue determination of veterinary drugs in milk by UHPLC-MS/MS. Analytical and Bioanalytical Chemistry, 411(7), 1433-1442.

Gilbert-López, B., Lara-Ortega, F.J., Robles-Molina, J., Brandt, S., Schütz, A., Moreno-González, D., García-Reyes, J.F., Molina-Díaz, A., & Franzke, J. (2019). Detection of multiclass explosives and related compounds in soil and water by liquid chromatography-dielectric barrier discharge ionization-mass spectrometry. Analytical and Bioanalytical Chemistry, 411(19), 4785-4796.

Jiménez Márquez, A., & Beltrán Maza, G. (2019). Gray-level Co-Occurrence Matrix application to Images Processing of crushed Olives fruits. Revista Iberoamericana de Inteligencia Artificial, 22(64), 135–142.

Nabet, N., Gilbert-López, B., Madani, K., Herrero, M., Ibáñez, E., & Mendiola, J.A. (2019). Optimization of microwave-assisted extraction recovery of bioactive compounds from Origanum glandulosum and Thymus fontanesii. Industrial Crops and Products, 129, 395-404.

Rascón, A.J., Azzouz, A., & Ballesteros-Tribaldo, E.A. (2019). Use of semi-automated continuous solid-phase extraction and gas chromatography-mass spectrometry for the determination of polycyclic aromatic hydrocarbons in alcoholic and non-alcoholic drinks from Andalucia (Spain). Journal of the Science of Food and Agriculture, 99(3), 1117-1125.

Rodríguez-Ortega, P.G., Gilbert-López, B., Esteo-Donaire, S., & Montejo-Gámez, M. (2019). Study of the effect of volume contraction in methanol-water mixtures used as solvents for analytical purposes: a student-centered project for practical learning. Journal of Chemical Education, 96(4), 677-684.


Alcántara-Durán, J., Moreno-González, D., Beneito-Cambra, M., & García-Reyes, J.F. (2018). Dilute-and-shoot coupled to nanoflow liquid chromatography high resolution mass spectrometry for the determination of drugs of abuse and sport drugs in human urine. Talanta, 182, 218–224.

Alcántara-Durán, J., Moreno-González, D., Gilbert-López, B., Molina-Díaz, A., & García-Reyes, J.F. (2018). Matrix-effect free multi-residue analysis of veterinary drugs in food samples of animal origin by nanoflow liquid chromatography high resolution mass spectrometry. Food chemistry, 245, 29–38.

Azzouz, A., Kailasa, S.K., Lee, S.S., Rascón, A.J., Ballesteros-Tribaldo, E.A., Zhang, M., & Kim, K-H. (2018). Review of nanomaterials as sorbents in solid-phase extraction for environmental samples. TrAC Trends in Analytical Chemistry, 108, 347-369.

Bejaoui, M.A., Sánchez-García, A., Aguilera, M.P., Ruiz-Moreno, M.J., Sánchez-Villasclaras, S., Jiménez, A., & Beltrán-Maza, G. (2018). High power ultrasound frequency for olive paste conditioning: effect on the virgin olive oil bioactive compounds and sensorial characteristics.  Innovative Food Science & Emerging Technologies, 47, 136-145.

Borbála-Both, E., Moreno-González, D., García-Reyes, J.F., & Dernovics, M. (2018). Monitoring the degradation of atropine and scopolamine in soil after spiking with naturally contaminated organic millet. The Science of the total environment, 625, 1088–1092.

Domínguez-Romero, J.C., Gilbert-López, B., Beneito-Cambra, M., & Molina-Díaz, A. (2018). Renewable chemiluminescence optosensors based on implementation of bead injection principle with multicommutation. Talanta, 182, 267-272.

Funes, E., Allouche, Y., Beltrán, G., Aguilera, M.P., & Jiménez, A. (2018). Predictive ANN models for the optimization of extra virgin olive oil clarification by means of vertical centrifugation. Journal of Food Process Engineering, 41(1), Article e12593.

Gila, A., Bejaoui, M.A., Beltrán, G., Aguilera, M.P., & Jiménez, A. (2018). Study of virgin olive oil clarification by settling under dynamic conditions. Journal of the science of food and agriculture, 98(14), 5361–5367.

Grande-Martínez, Á., Moreno-González, D., Arrebola-Liébanas, F.J., Garrido-Frenich, A., & García-Campaña, A.M. (2018). Optimization of a modified QuEChERS method for the determination of tetracyclines in fish muscle by UHPLC-MS/MS. Journal of pharmaceutical and biomedical analysis, 155, 27–32.

Lara-Ortega, F.J., Beneito-Cambra, M., Robles-Molina, J., García-Reyes, J.F., Gilbert-López, B., & Molina-Díaz, A. (2018). Direct olive oil analysis by mass spectrometry: A comparison of different ambient ionization methods. Talanta, 180, 168–175.

Lara-Ortega, F.J., Gilbert-López, B., Beneito-Cambra, M., & Molina-Díaz, A. (2018). Multicommuted flow injection analysis using chemiluminescence detection (MCFIA-CL) for olive oil analysis. Food Analytical Methods, 11, 1804-1814.

Lara-Ortega, F.J., Robles-Molina, J., Brandt, S., Schütz, A., Gilbert-López, B., Molina-Díaz, A., García-Reyes, J.F., & Franzke, J. (2018). Use of dielectric barrier discharge ionization to minimize matrix effects and expand coverage in pesticide residue analysis by liquid chromatography-mass spectrometry. Analytica Chimica Acta, 1020, 76-85.

López-Blanco, R., Moreno-González, D., Nortes-Méndez, R., García-Reyes, J.F., Molina-Díaz, A., & Gilbert-López, B. (2018). Experimental and theoretical determination of pesticide processing factors to model their behaviour during virgin olive oil production. Food Chemistry, 239, 9-16.

Montero, L., Sánchez-Camargo, A.P., Ibáñez, E., & Gilbert-López, B. (2018). Phenolic Compounds from Edible Algae: Bioactivity and Health Benefits. Current medicinal chemistry, 25(37), 4808–4826.

Moreno-González, D., Alcántara-Durán, J., Addona, S.M., & Beneito-Cambra, M. (2018). Multi-residue pesticide analysis in virgin olive oil by nanoflow liquid chromatography high resolution mass spectrometry. Journal of Chromatography A, 1562, 27-35.

Moreno-González, D., Alcántara-Durán, J., Gilbert-López, B., Beneito-Cambra, M., Cutillas, V.M., Rajski, Ł., Molina-Díaz, A., & García-Reyes, J.F. (2018). Sensitive Detection of Neonicotinoid Insecticides and Other Selected Pesticides in Pollen and Nectar Using Nanoflow Liquid Chromatography Orbitrap Tandem Mass Spectrometry. Journal of AOAC International, 101(2), 367–373.

Moreno-González, D., Krulišová, M., Gámiz-Gracia, L., & García-Campaña, A.M. (2018). Determination of tetracyclines in human urine samples by capillary electrophoresis in combination with field amplified sample injection. Electrophoresis, 39(4), 608-615.

Quintero-Flórez, A., Pereira-Caro, G., Sánchez-Quezada, C., Moreno-Rojas, J.M., Gaforio, J.J., Jiménez, A., & Beltrán, G. (2018). Effect of olive cultivar on bioaccessibility and antioxidant activity of phenolic fraction of virgin olive oil. European journal of nutrition, 57(5), 1925–1946.

Rascón, A.J., Azzouz, A., & Ballesteros-Tribaldo, E.A. (2018). Determination of polycyclic aromatic hydrocarbons in environmental waters from southern spain by using a continuous solid-phase extraction system and gas chromatography-mass spectrometry. Environmental Chemistry, 15(6), 351-361.

Rascón, A.J., Azzouz, A., & Ballesteros-Tribaldo, E.A. (2018). Multiresidue determination of polycyclic aromatic hydrocarbons in edible oils by liquid-liquid extraction-solid-phase extraction-gas chromatography-mass spectrometry. Food Control, 94, 268-275.

Sánchez-Camargo, A.P., Pleite, N., Mendiola, J.A., Cifuentes, A.,  Herrero, M., Gilbert-López, B., & Ibáñez, E. (2018). Development of green extraction processes for Nannochloropsis gaditana biomass valorization. Electrophoresis, 39(15), 1875-1883.

Sánchez-Ortiz, A., Bejaoui, M.A., Quintero-Flores, A., Jiménez, A., & Beltrán, G. (2018). "Biosynthesis of volatile compounds by hydroperoxide lyase enzymatic activity during virgin olive oil extraction process". Food Research international (Ottawa, Ont.), 111, 220–228.

Tripodo, G., Ibáñez, E., Cifuentes, A., Gilbert-López, B., & Fanali, C. (2018). Optimization of pressurized liquid extraction by response surface methodology of Goji berry (Lycium barbarum L.) phenolic bioactive compounds. Electrophoresis, 39(13), 1673–1682.

Valverde-Som, L., Carrasco-Pancorbo, A., Sierra, S., Santana, S., Ruiz-Samblás, C., Navas, N., Burgos, J.S., & Cuadros-Rodríguez, L. (2018). Separation and determination of some of the main cholesterol-related compounds in blood by gas chromatography-mass spectrometry (Selected lon monitoring mode). Separations, 5(1), Article 17.

Valverde-Som, L., Ruiz-Samblás, C., & Rodríguez-García, F.P. (2018). Multivariate approaches for stability control of the olive oil reference materials for sensory analysis-part I: framework and fundamentals. Journal of the Science of Food and Agriculture, 98(11), 4237-4244.

Valverde-Som, L., Ruiz-Samblás, C., Rodríguez-García, F.P., & Cuadros-Rodríguez, L. (2018). Multivariate approaches for stability control of the olive oil reference materials for sensory analysis - part II: applications. Journal of the science of food and agriculture, 98(11), 4245–4252.

Instrumento estratégico hacia un tejido productivo,  Agroalimentario, Moderno, Innovador y  Sostenible: motor del territorio rural andaluz: Desarrollo de bioindicadores que determinen el perfil físico-químico y sensorial de los aceites de oliva vírgenes

Entidad Financiadora: Campus de Excelencia Internacional en Agroalimentación. Proyecto singular AgroMIS

Referencia: A1122062E0_AGROMIS ceiA3-UCO 2019

Investigador principal: Antonio Molina Díaz

Año de inicio: 2020

Presupuesto: 35.000,00 €


Implementación de nuevos dispositivos de ionización por descarga de barrera dieléctrica en metabolómica y seguridad alimentaria

Entidad Financiadora: Junta de Andalucía-Universidad de Jaén (Proyecto FEDER-UJA)

Referencia: 1264521

Investigador principal: Antonio Molina Díaz

Año de inicio: 2020

Presupuesto: 79.962,82 €


Clasificación de aceites de oliva de diferentes categorías comerciales mediante espectrometría de masas de alta resolución y aproximaciones de metabolómica no dirigida

Entidad Financiadora: Junta de Andalucía-Universidad de Jaén (Proyecto FEDER-UJA)

Referencia: 1263809

Investigador principal: David Moreno González

Año de inicio: 2020

Presupuesto: 97.000,00 €


Novel approaches to promote the sustainability of Olive groves in the Mediterranean (SUSTAINOLIVE)         

Entidad financiadora: Convocatoria Europea PRIMA (Partnership for Research and Innovation in the Mediterranean Area). Cofinanciado con fondos Horizon 2020 Framework Programme of the European Union

Referencia: Farming System 9

Investigador principal: Roberto García Ruiz                  

Año de inicio: 2019

Presupuesto: 2.032.690,17 €


Desarrollo de nuevas aproximaciones basadas en basadas en cromatografía-espectrometría de masas para la resolución de problemas de gran interés social en el campo de la calidad y la seguridad alimentaria del aceite de oliva

Entidad Financiadora: Ayudas a la I+D+i, en el ámbito del Plan Andaluz de Investigación, Desarrollo e Innovación, PAIDI

Referencia: P18-RT-1211

Investigador principal: Antonio Molina Díaz

Año de inicio: 2020

Presupuesto: 140.500,00 €


Advancing mass spectrometry: Ionization and applications

Entidad Financiadora: Acciones de dinamización de carácter internacional “EUROPA INVESTIGACIÓN”. Programa Estatal de investigación, desarrollo e innovación orientada a los retos de la sociedad

Referencia: EUIN2017-88337

Investigador principal: Juan Francisco García Reyes

Año de inicio: 2018

Presupuesto: 22.500,00 €


Twinning in atmospheric Plasma science and applications (TImPANI)

Entidad Financiadora: Horizonte 2020. Prorama Twinning of research institutions

Referencia: H2020-EU.4.b. - 810686

Investigador principal: George Georgiou

Año de inicio: 2018

Presupuesto: 999.625,00 €


Nuevas aproximaciones experimentales a la solución de las limitaciones actuales de la cromatografía de líquidos/espectrometría de masas (LC-MS) en análisis de contaminantes

Entidad Financiadora: Concesión de ayudas a «Proyectos de I+D+i», en el marco del Programa Estatal de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico del Sistema de I+D+i y del Programa Estatal de I+D+i Orientada a los Retos de la Sociedad, del Plan Estatal de Investigación Científica y Técnica y de Innovación 2015

Referencia: CTQ-2015-71321-P

Investigadores principales: Antonio Molina Díaz y Juan Francisco García Reyes

Año de inicio: 2016

Presupuesto: 67.518,00 €

Private companies and public institutions related to the olive oil and olive sector

Technical advice in chemistry

unit members

Juan Francisco
García Reyes

Head of Unit

Antonio Molina Díaz

Senior Researcher

Molina Díaz

Senior Researcher

Evaristo Antonio
Ballesteros Tribaldo

Senior Researcher

Bienvenida Gilbert López

Senior Researcher

Gilbert López

Senior Researcher

Moreno González


Castilla Fernández


Bouza Areces


Rocío Bautista


Andrés Jesús
Rascón López


García Martínez


Fernández García


Caño Carrillo


Antonio Jiménez Márquez

External Collaborator Researcher

Jiménez Márquez

External Collaborator Researcher

research units

The INUO is structured into Research Units that bring together an amalgamation of researchers, which although they may belong to different subareas of knowledge, the name of each Unit corresponds to the main lines of research characteristic of the Institute and are as follows:

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